Novel FX Missense Variant Analysis

  • The effects of any undescribed missense variants may be predicted here.
  • Codons are numbered with respect to HGVS nomenclature, with codon 1 representing the first residue (Met) of the signal peptide: type in your codon number of interest.
  • You may select any one option for the "Variant Amino-Acid".

Multiple Sequence Alignment of putative FX protein sequences from six selected primate species    

Note: if alignments fail to display on a PC, please try using Internet Explorer (easily accessible from Start Menu/Programs/Windows Accessories), or use a browser on a Mac or iPad. You can also download a PDF of the alignment by clicking HERE.

Note: Dragging the mouse over the sequences will take you across the sequence limits
Note: AA numbering is for human FX and is HGVS

FX HUMAN P00742 | FX CHIMPANZEE H2Q7T9| FX GORILLA G3RDY3| FX GIBBON A0A2I3HV74
FX BUSHBABY B5SNI2| FX MARMOSET B0KW84